Polynucleotides are injectable, highly purified products usually derived from fish, such as salmon or trout. They are incorporated into a polymerised injectable gel, upon injection polynucleotides bind with skin cells to make skin tissue firmer and more hydrated.

Often referred to as "biostimulators," polynucleotides possess anti-free radical properties and act as scavengers of hydroxyl radicals, which accumulate due to stress and UV exposure. Their hydration and anti-free radical effects help create an optimal environment for fibroblast growth, essential for producing collagen, elastin, and hyaluronic acid, which contribute to resilient skin.

The use of polynucleotides for under-eye treatments is transforming cosmetic procedures. Many doctors report that patients with concerns about their under-eye area—who might not qualify for tear-trough fillers due to issues like under-eye bags or tissue elasticity—can see significant improvements with polynucleotides. For those already receiving tear-trough fillers for hollowing, integrating polynucleotides into the treatment plan can extend the time between filler sessions.

How do Polynucleotides work?

Polynucleotides are gaining attention for their regenerative properties. These long chains of nucleotides, naturally found in DNA and RNA, work by supporting cellular repair and renewal. When applied to the skin, polynucleotides stimulate collagen production, improve hydration, and enhance skin elasticity. They promote a healthier, more youthful appearance by boosting the skin's natural ability to heal and regenerate, making them a valuable ingredient in treatments targeting ageing, scarring, and overall skin rejuvenation.